Dim char_array_end = "<br />".ToCharArray Dim char_array_start = "I ".ToCharArray Dim my_string = "I love pizza, beer, sambuca<br />" Dim my_string_trimmed = my_string.TrimEnd(char_array_end) Console.WriteLine(my_string_trimmed) 'I love pizza, beer, sambuca' my_string_trimmed = my_string.TrimStart(char_array_start) Console.WriteLine(my_string_trimmed) 'love pizza, beer, sambuca<br />'